Lead has a very stable nucleolus. Forever chemicals (PFAS) were named that because they were stable. CFCs were pretty harmless too until we learned about ozone layer.

Anything that industry makes and distributes in large quantities throughout the world is pretty bad because by the time we learn about long term impacts, it’s everywhere

If it’s not we got something from virus that helped us, and chimps got something that limited them. Then it’s funnily possible for a global pandemic to make our whole population stupid. Normally evolution would work out and smarter population would do better, but for us it depends on which side has nukes. So …